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1

Platelet-dependent stimulation of prostacyclin synthesis by platelet-derived growth factor

Coughlin, Shaun R., Moskowitz, Michael A., Zetter, Bruce R., Antoniades, Harry N., Levine, Lawrence

Journal:

Year:

1980

File:

PDF, 397 KB

1980

2

Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia

Jean B. Regard, Natasha Cherman, Daniel Palmer, Sergei A. Kuznetsov, Francesco S. Celi, Jean-Marc Guettier, Min Chen, Nisan Bhattacharyya, Jurgen Wess, Shaun R. Coughlin, Lee S. Weinstein, Michael T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

3

The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors

Lefrançais, Emma, Ortiz-Muñoz, Guadalupe, Caudrillier, Axelle, Mallavia, Beñat, Liu, Fengchun, Sayah, David M., Thornton, Emily E., Headley, Mark B., David, Tovo, Coughlin, Shaun R., Krummel, Matthew

Journal:

Year:

2017

Language:

english

File:

PDF, 8.81 MB

english, 2017

4

Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent

Ely, Lauren K., Lolicato, Marco, David, Tovo, Lowe, Kate, Kim, Yun Cheol, Samuel, Dharmaraj, Bessette, Paul, Garcia, Jorge L., Mikita, Thomas, Minor, Daniel L., Coughlin, Shaun R.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.93 MB

english, 2018

5

The stimulation of paracrine and autocrine mitogenic pathways by the platelet-derived growth factor receptor

Lewis T. Williams, Jaime A. Escobedo, Mark T. Keating, Shaun R. Coughlin

Journal:

Journal of Cellular Physiology

Year:

1987

Language:

english

File:

PDF, 366 KB

english, 1987

6

Better late than never? Impact of local analgesia timing on postoperative pain in laparoscopic surgery: a systematic review and metaanalysis

Shaun M. Coughlin, Paul J. Karanicolas, Heather M. A. Emmerton-Coughlin, Bilge Kanbur, Savas Kanbur, Patrick H. D. Colquhoun

Journal:

Surgical Endoscopy

Year:

2010

Language:

english

File:

PDF, 572 KB

english, 2010

7

10.1038/29325

Coughlin, Shaun R., Kahn, Mark L., Zheng, Yao-Wu, Huang, Wei, Bigornia, Violeta, Zeng, Dewan, Moff, Stephen, Farese, Robert V., Tam, Carmen

Journal:

Year:

1998

Language:

english

File:

PDF, 373 KB

english, 1998

8

10.1038/35007085

Coughlin, Shaun R., Nakanishi-Matsui, Mayumi, Zheng, Yao-Wu, Sulciner, David J., Weiss, Ethan J., Ludeman, Matthew J.

Journal:

Year:

2000

Language:

english

File:

PDF, 214 KB

english, 2000

9

10.1038/35025229

Coughlin, Shaun R.

Journal:

Year:

2000

Language:

english

File:

PDF, 256 KB

english, 2000

10

Domains specifying thrombin–receptor interaction

Vu, Thien-Khai H., Wheaton, Virginia I., Hung, David T., Charo, Israel, Coughlin, Shaun R.

Journal:

Year:

1991

File:

PDF, 458 KB

1991

11

Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface

Gerszten, Robert E., Chen, Ji, Ishli, Maki, Ishil, Kenji, Wang, Ling, Nanevicz, Tania, Turck, Christoph W., Vu, Thien-Khai H., Coughlin, Shaun R.

Journal:

Year:

1994

File:

PDF, 433 KB

1994

12

Role of the thrombin receptor in development and evidence for a second receptor

Connolly, Andrew J., Ishihara, Hiroaki, Kahn, Mark L., Farese, Robert V., Coughlin, Shaun R.

Journal:

Year:

1996

File:

PDF, 883 KB

1996

13

Protease-activated receptor 3 is a second thrombin receptor in humans

Ishihara, Hiroaki, Connolly, Andrew J., Zeng, Dewan, Kahn, Mark L., Wu Zheng, Yao, Timmons, Courtney, Tram, Tracy, Coughlin, Shaun R.

Journal:

Year:

1997

File:

PDF, 1.12 MB

1997

14

10.1038/35092573

Sambrano, Gilberto R., Weiss, Ethan J., Zheng, Yao-Wu, Huang, Wei, Coughlin, Shaun R.

Journal:

Year:

2001

Language:

english

File:

PDF, 251 KB

english, 2001

15

Somatostatin Analogues for the Treatment of Enterocutaneous Fistulas: A Systematic Review and Meta-analysis

Shaun Coughlin, Lee Roth, Giovanna Lurati, Markus Faulhaber

Journal:

World Journal of Surgery

Year:

2012

Language:

english

File:

PDF, 946 KB

english, 2012

16

Thrombin receptor function and cardiovascular disease

Shaun R. Coughlin

Journal:

Trends in Cardiovascular Medicine

Year:

1994

Language:

english

File:

PDF, 5.27 MB

english, 1994

17

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

Jeffrey L. Brown, Lisa Stowers, Margaret Baer, JoAnn Trejo, Shaun Coughlin, John Chant

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 283 KB

english, 1996

18

A SAGE Approach to Discovery of Genes Involved in Autophagic Cell Death

Sharon M. Gorski, Suganthi Chittaranjan, Erin D. Pleasance, J.D. Freeman, Carrie L. Anderson, Richard J. Varhol, Shaun M. Coughlin, Scott D. Zuyderduyn, Steven J.M. Jones, Marco A. Marra

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

19

TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

Huanghe Yang, Andrew Kim, Tovo David, Daniel Palmer, Taihao Jin, Jason Tien, Fen Huang, Tong Cheng, Shaun R. Coughlin, Yuh Nung Jan, Lily Yeh Jan

Journal:

Year:

2012

File:

PDF, 87 KB

2012

20

JE Gene Expression in an Animal Model of Acute Arterial Graft Rejection

F.Frank Isik, Shaun R. Coughlin, Nicolas A. Nelken, Alexander W. Clowes, David Gordon

Journal:

Journal of Surgical Research

Year:

1996

Language:

english

File:

PDF, 398 KB

english, 1996

21

Identification of a serotonin type 2 receptor linked to prostacyclin synthesis in vascular smooth muscle cells

Shaun R. Coughlin, Michael A. Moskowitz, Lawrence Levine

Journal:

Biochemical Pharmacology

Year:

1984

Language:

english

File:

PDF, 469 KB

english, 1984

22

Anatomical Profiling of G Protein-Coupled Receptor Expression

Jean B. Regard, Isaac T. Sato, Shaun R. Coughlin

Journal:

Year:

2008

Language:

english

File:

PDF, 755 KB

english, 2008

23

Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids

Songzhu An, Thieu Bleu, Wei Huang, Olivia G Hallmark, Shaun R Coughlin, Edward J Goetzl

Journal:

Year:

1997

Language:

english

File:

PDF, 495 KB

english, 1997

24

High-resolution crystal structure of human protease-activated receptor 1

Zhang, Cheng, Srinivasan, Yoga, Arlow, Daniel H., Fung, Juan Jose, Palmer, Daniel, Zheng, Yaowu, Green, Hillary F., Pandey, Anjali, Dror, Ron O., Shaw, David E., Weis, William I., Coughlin, Shaun R.,

Journal:

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

25

P-127 Transcriptome profiling technologies at the British Columbia Cancer Agency

Khattra, Jaswinder, Chan, Susanna, Asano, Jennifer, Pandoh, Pawan, Coughlin, Shaun, McDonald, Helen, Girn, Noreen, Jones, Steven, Marra, Marco

Journal:

Year:

2003

Language:

english

File:

PDF, 381 KB

english, 2003

26

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

Thien-Khai H. Vu, David T. Hung, Virginia I. Wheaton, Shaun R. Coughlin

Journal:

Year:

1991

Language:

english

File:

PDF, 1.51 MB

english, 1991

27

Dual trophic effects of the alpha1-adrenergic receptor in cultured neonatal rat heart muscle cells

Paul Simpson, Nanette Bishopric, Shaun Coughlin, Joel Karliner, Charles Ordahl, Niel Starksen, Tanny Tsao, Neal White, Lewis Williams

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1986

Language:

english

File:

PDF, 748 KB

english, 1986

28

Serotonin-induced mitogenesis in vascular smooth muscle cells involves a novel, pertussis toxin-sensitive pathway

W. Michael Kavanaugh, Shaun R. Coughlin, Harlan E. Ives, Lewis T. Williams

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1987

Language:

english

File:

PDF, 86 KB

english, 1987

29

Protease-Activated Receptor 2, Dipeptidyl Peptidase I, and Proteases Mediate Clostridium difficile Toxin A Enteritis

Graeme S. Cottrell, Silvia Amadesi, Stella Pikios, Eric Camerer, J. Adam Willardsen, Brett R. Murphy, George H. Caughey, Paul J. Wolters, Shaun R. Coughlin, Anders Peterson, Wolfgang Knecht, Charalabo

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 8.01 MB

english, 2007

30

Expanding horizons for receptors coupled to G proteins: diversity and disease

Coughlin, Shaun R.

Journal:

Current Opinion in Cell Biology

Year:

1994

Language:

english

File:

PDF, 723 KB

english, 1994

31

Su1559 Somatostatin Analogues for the Treatment of Enterocutaneous Fistulas: A Systematic Review and Meta-Analysis

Coughlin, Shaun

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 80 KB

english, 2012

32

Tmem16F forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

Yang, Huanghe, Kim, Andrew, David, Tovo, Palmer, Daniel, Jin, Taihao, Tien, Jason, Huang, Fen, Cheng, Tong, Coughlin, Shaun, Nung Jan, Yuh, Jan, Lily Y.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 42 KB

english, 2013

33

[Part 2: Biological Sciences] || Serotonin Receptor-Mediated Stimulation of Bovine Smooth Muscle Cell Prostacyclin Synthesis and Its Modulation by Platelet-Derived Growth Factor

Shaun R. Coughlin, Michael A. Moskowitz, Harry N. Antoniades and Lawrence Levine

Journal:

Proceedings of the National Academy of Sciences

Year:

1981

Language:

english

File:

PDF, 830 KB

english, 1981

34

[Part 1: Biological Sciences] || Blockade of Autocrine Stimulation in Simian Sarcoma Virus-Transformed Cells Reverses Down-Regulation of Platelet-Derived Growth Factor Receptors

Jeremy S. Garrett, Shaun R. Coughlin, Henry L. Niman, Patrice M. Tremble, Gertrude M. Giels and Lewis T. Williams

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 1.51 MB

english, 1984

35

Stimulation of Aortic Smooth Muscle Cell Mitogenesis by Serotonin

Georgina M. Nemecek, Shaun R. Coughlin, Dean A. Handley and Michael A. Moskowitz

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.16 MB

english, 1986

36

Cardiac Myocyte Hypertrophy is Associated with c-myc Protooncogene Expression

Niel F. Starksen, Paul C. Simpson, Nannette Bishopric, Shaun R. Coughlin, William M. F. Lee, Jaime A. Escobedo and Lewis T. Williams

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 453 KB

english, 1986

37

Termination of Signaling by Protease-Activated Receptor-1 is Linked to Lysosomal Sorting

JoAnn Trejo, Stephen R. Hammes and Shaun R. Coughlin

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.52 MB

english, 1998

38

How the Protease Thrombin Talks to Cells

Shaun R. Coughlin

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 836 KB

english, 1999

39

The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement

Green, Jesse A, Suzuki, Kazuhiro, Cho, Bryan, Willison, L David, Palmer, Daniel, Allen, Christopher D C, Schmidt, Timothy H, Xu, Ying, Proia, Richard L, Coughlin, Shaun R, Cyster, Jason G

Journal:

Nature Immunology

Year:

2011

Language:

english

File:

PDF, 2.08 MB

english, 2011

40

Thrombin-Induced Events in Non-Platelet Cells Are Mediated by the Unique Proteolytic Mechanism Established for the Cloned Platelet Thrombin Receptor

David T. Hung, Thien-Khai H. Vu, Nicolas A. Nelken and Shaun R. Coughlin

Journal:

The Journal of Cell Biology

Year:

1992

Language:

english

File:

PDF, 1.31 MB

english, 1992

41

Protease-Activated Receptor-1 Can Mediate Responses to SFLLRN in Thrombin-Desensitized Cells: Evidence for a Novel Mechanism for Preventing or Terminating Signaling by PAR1's Tethered Ligand †

Hammes, Stephen R., Coughlin, Shaun R.

Journal:

Year:

1999

Language:

english

File:

PDF, 134 KB

english, 1999

42

Shutoff and Agonist-Triggered Internalization of Protease-Activated Receptor 1 Can Be Separated by Mutation of Putative Phosphorylation Sites in the Cytoplasmic Tail †

Hammes, Stephen R., Shapiro, Michael J., Coughlin, Shaun R.

Journal:

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

43

A critical role for extracellular protein disulfide isomerase during thrombus formation in mice

Cho, Jaehyung, Furie, Barbara C., Coughlin, Shaun R., Furie, Bruce

Journal:

Journal of Clinical Investigation

Year:

2008

Language:

english

File:

PDF, 1.30 MB

english, 2008

44

High-concentration oxygen and surgical site infections in abdominal surgery: a meta-analysis

Patel, Sunil, Coughlin, Shaun, Malthaner, Richard

Journal:

Canadian Journal of Surgery

Year:

2013

File:

PDF, 311 KB

2013

45

Management of chest tubes after pulmonary resection: a systematic review and meta-analysis

Coughlin, Shaun, Emmerton-Coughlin, Heather, Malthaner, Richard

Journal:

Canadian Journal of Surgery

Year:

2012

File:

PDF, 274 KB

2012

46

Imaging G protein–coupled receptors while quantifying their ligand-binding free-energy landscape

Alsteens, David, Pfreundschuh, Moritz, Zhang, Cheng, Spoerri, Patrizia M, Coughlin, Shaun R, Kobilka, Brian K, Müller, Daniel J

Journal:

Year:

2015

Language:

english

File:

PDF, 1.93 MB

english, 2015

47

Entry from the Lipid Bilayer: A Novel Pathway for Inhibition of a Peptide G-Protein Coupled Receptor by a Lipophilic Small Molecule

Bokoch, Michael P., Jo, Hyunil I., Valcourt, James R., Srinivasan, Yoga, Yasuhara, Kazuma, Pan, Albert C., Dror, Ron O., Shaw, David E., DeGrado, William F., Coughlin, Shaun R.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 42 KB

english, 2015

48

Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography

Page, Michael J., Lourenço, André L., David, Tovo, LeBeau, Aaron M., Cattaruzza, Fiore, Castro, Helena C., VanBrocklin, Henry F., Coughlin, Shaun R., Craik, Charles S.

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 2.04 MB

english, 2015

49

Expression Cloning and Characterization of a Functional Thrombin Receptor Reveals a Novel Proteolytic Mechanism of Receptor Activation

Coughlin, Shaun, Vu, Thien-khai, Hung, David, Wheaton, Virginia

Journal:

Seminars in Thrombosis and Hemostasis

Year:

1992

Language:

english

File:

PDF, 944 KB

english, 1992

50

Molecular Cloning and Functional Expression of Two Monocyte Chemoattractant Protein 1 Receptors Reveals Alternative Splicing of the Carboxyl-Terminal Tails

Israel F. Charo, Scott J. Myers, Ann Herman, Christian Franci, Andrew J. Connolly and Shaun R. Coughlin

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.04 MB

english, 1994

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